Mastelli Plinest One

Plinest One is an injectable preparation for biorevitalization developed by the Italian company Mastelli. It is based on polynucleotides (PDRN) derived from salmon milk and is intended to improve skin quality, increase its firmness and elasticity, as well as reduce signs of aging.

Main characteristics:

    Composition: Polydeoxyribonucleotide (PDRN) with a concentration of 2 mg/ml.
    Volume: 4 ml vials.
    Indications: Dry, sagging skin, wrinkles, loss of firmness, stretch marks, scars.
    Contraindications: Oncological diseases, fish allergy, decompensated diabetes, epilepsy, autoimmune diseases, blood clotting disorders, dermatoses.

Mechanism of action:

    DNA restoration: PDRN promotes the restoration of damaged DNA in dermal cells.
    Fibroblast stimulation: Activates fibroblast proliferation, enhancing collagen and elastin synthesis.
    Microcirculation improvement: Promotes the formation of new blood vessels, improving tissue nutrition and oxygen supply.
    Antioxidant effect: Protects cells from oxidative stress and slows down aging processes.

Procedure protocol:

    Treatment course: 3–4 sessions with intervals of 2–3 weeks.
    Dosage: 2–4 ml per session depending on the injection area.
    Maintenance therapy: 1 session every 4–6 months.

Recommended areas of application:

    Face: Dull, dehydrated, or sagging skin.
    Neck and décolleté: Wrinkles, loss of firmness.
    Hands: Signs of aging, dryness.

Results of use:

    Hydration: Deep and noticeable after the first procedure.
    Firmness: The skin becomes denser and more elastic.
    Natural effect: Results last up to 6–8 months.